Familial Absorptive Hypercalciuria in a Large Kindred

Abstract

No AccessJournal of UrologyOriginal Articles1 Dec 1981Familial Absorptive Hypercalciuria in a Large Kindred Charles Y.C. Pak, James McGuire, Roy Peterson, Faye Britton, and Mary Jo Harrod Charles Y.C. PakCharles Y.C. Pak , James McGuireJames McGuire , Roy PetersonRoy Peterson , Faye BrittonFaye Britton , and Mary Jo HarrodMary Jo Harrod View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)54715-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The occurrence of calcareous renal stones in 12 members of a family was consistent with an autosomal dominant mode of inheritance. All 6 members with stones who were evaluated were shown to have absorptive hypercalciuria. The mother of 2 members with stones did not suffer stones but had biochemical evidence of absorptive hypercalciuria (increased intestinal calcium absorption, hypercalciuria and normal parathyroid function). Nephrolithiasis was encountered only in the progeny of members who had stones or biochemical absorptive hypercalciuria. The results suggest that physiological feature(s) of absorptive hypercalciuria may be an expression of the genetic trait. © 1981 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByVezzoli G, Soldati L and Gambaro G (2018) Update on Primary Hypercalciuria From a Genetic PerspectiveJournal of Urology, VOL. 179, NO. 5, (1676-1682), Online publication date: 1-May-2008.Pak C (2018) Medical Stone Management: 35 Years of AdvancesJournal of Urology, VOL. 180, NO. 3, (813-819), Online publication date: 1-Sep-2008.Nicolaidou P, Themeli S, Karpathios T, Georgouli H, Athanassaki K, Xaidara A and Messaritakis J (2018) Family Pattern of Idiopathic Hypercalciuria and its SubtypesJournal of Urology, VOL. 155, NO. 3, (1042-1044), Online publication date: 1-Mar-1996.Favus M (2018) Familial Forms of HypercalciuriaJournal of Urology, VOL. 141, NO. 3 Part 2, (719-722), Online publication date: 1-Mar-1989.Pak C, Sakhaee K, Hwang T, Preminger G and Harvey J (2018) Nephrolithiasis from Calcium SupplementationJournal of Urology, VOL. 137, NO. 6, (1212-1213), Online publication date: 1-Jun-1987. Volume 126Issue 6December 1981Page: 717-719 Advertisement Copyright & Permissions© 1981 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Charles Y.C. Pak More articles by this author James McGuire More articles by this author Roy Peterson More articles by this author Faye Britton More articles by this author Mary Jo Harrod More articles by this author Expand All Advertisement PDF DownloadLoading ...