Mapping of the Growth Hormone Gene by in situ Hybridization to Chicken Chromosome 1

Abstract

In situ hybridization of a tritium-labeled chicken growth hormone cDNA to 62 chicken metaphase chromosome spreads was examined by analysis of silver grain distribution. A total of 554 chromosomally located grains were recorded. There was a highly significant P value for the association of silver grains to the long arm of chromosome 1. The chicken growth hormone gene can be assigned to chromosomal G-band region 1q4 because 41.3% of silver grains on chromosome 1q were located in this region.