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Lipid accumulation stimulates the cap-independent translation of SREBP-1a mRNA by promoting hnRNP A1 binding to its 5′-UTR in a cellular model of hepatic steatosis

Transcriptional RegulationSignal TransductionBiochemistryLipid AccumulationNatural SciencesLiver PhysiologyMetabolic SignalingSrebp-1a MrnaMetabolic RegulationHnrnp A1 BindingLiver DiseaseFatty Liver DiseaseCellular BiochemistryGene ExpressionMedicineCell BiologyCell SignalingLipid Synthesis