Journal of Polymer Engineering · 1988 · 13 citations · 12 references
PharmacyPharmaceuticsDrug DeliveryOral Drug DeliveryPharmaceutical TechnologyControlled Release MechanismsDrug Delivery SystemsDrug DistributionDrug FormulationDrug Release From Dosage FormsDrug Release KineticsDiffusivityDrug - Polymer InteractionsDrug Diffusion In PolymersDrug Diffusion KineticsDrug Diffusion ModelingDrug Release ModelingPolymer Matrix ReleasePolymeric Drug Release
Study of the release of the drug from polymeric forms, spherical in shape, prepared by dispersing the drug (sodium salicylate) in Eudragit as polymer matrix. Some parameters of interest are especially examined: the diameter of forms, the concentration of drug, the pH of synthetic gastric liquid. The dependence of the durg diffusivity on the concentration of the liquid in polymer is determined by using several samples with various concentrations of drug ranging from 25 to 75 (weight %)
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Analysis of Fickian and non-Fickian drug release from polymers.
Nicholas A. Peppas · PubMed · 1985 · 2.1K citations