<i>CELF4</i> Variant and Anthracycline-Related Cardiomyopathy: A Children’s Oncology Group Genome-Wide Association Study - Concepedia

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<i>CELF4</i> Variant and Anthracycline-Related Cardiomyopathy: A Children’s Oncology Group Genome-Wide Association Study

DOI Full Paper Access

131

Citations

29

References

2016

Year

Xuexia Wang, Can-Lan Sun, Adolfo Quiñones‐Lombraña, Purnima Singh, Wendy Landier, Lindsey Hageman, Molly A. Mather, Jerome I. Rotter, Kent D. Taylor, Yii-Der Ida Chen,

Journal of Clinical Oncology

Abstract

We report a modifying effect of a polymorphism of CELF4 (rs1786814) on the dose-dependent association between anthracyclines and cardiomyopathy, which possibly occurs through a pathway that involves the expression of abnormally spliced TNNT2 variants.

References

	Year	Citations

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