Indian Journal of Pharmaceutical Sciences · 1996 · 24 citations · 0 references
MedicineImmunologyPharmacologyEthnobotanyFood ChemistryInflammationAnti-inflammatory PharmacologyGranulomatous InflammationInflammation PharmacologyMedicinal Plant KnowledgeAnti-inflammatory ActivityAnti-inflammatory Natural ProductsExtractive DistillationMedicinal Aromatic PlantsSteam Distillation
Oil of Toddalia asiatica leaves obtained by steam distillation was given orally to study its effects on the exudative and proliferative phases of the inflammatory reactions, using the technique of carrageenin induced paw edema and cotton pellets in male albino rats. The antiinflammatory activity was compared with ketorolac tromethamine. In carrageenin-induced paw edema, 0.8 ml/kg of the volatile oil showed antiinflammatory activity comparable to that of ketorolac tromethamine. The oil was also found to be effective in cotton pellet granuloma studies.