Publication | Open Access

The Deoxynucleoside Triphosphate Triphosphohydrolase Activity of SAMHD1 Protein Contributes to the Mitochondrial DNA Depletion Associated with Genetic Deficiency of Deoxyguanosine Kinase

Deoxyguanosine KinaseMitochondrial FunctionBiochemistryNatural SciencesGeneticsDna ReplicationMolecular BiologyMitochondrial MedicineMolecular GeneticsGenetic DeficiencySamhd1 ProteinMedicineRedox BiologyProtein PhosphorylationOxidative Stress