Preclinical and initial clinical evaluation of 111In-labeled nonsulfated CCK8 analog: a peptide for CCK-B receptor-targeted scintigraphy and radionuclide therapy. - Concepedia

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Preclinical and initial clinical evaluation of 111In-labeled nonsulfated CCK8 analog: a peptide for CCK-B receptor-targeted scintigraphy and radionuclide therapy.

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References

1999

Year

M. de Jong, Willem H. Bakker, Bert F. Bernard, Roelf Valkema, D. J. Kwekkeboom, J.C. Reubi, A. Srinivasan, Michelle Schmidt, E. P. Krenning

Abstract

[111In-DOTA0]CCK8 is most promising for scintigraphy and, after coupling to therapeutic radionuclides, for radionuclide therapy of human CCK-B receptor-positive tumors such as MTC and small cell lung cancer.