NIOSOMAL WITHAFERIN A WITH BETTER ANTITUMOR EFFICACY

I. P Seena, U. V. Singh, Raghavendra C. Kamath, P. Uma Devi, N Udupa

Indian Journal of Pharmaceutical Sciences · 1998 · 16 citations · 0 references

Concepts

Abstract

Withaferin A was entrapped in niosomes. The release of the drug from the niosome was slower compared to plain withaferin A dispersed in phosphate buffered saline. The mean survival time (MST) of the animals treated with withaferin A entrapped in the niosome was enhanced compared to the plain drug.