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CHROMOSOMAL STUDIES IN SOME VARIANTS OF MALE PSEUDOHERMAPHRODITISM
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References
1961
Year
CytogeneticsGeneticsMolecular GeneticsReproductive BiologyEpigeneticsMale PseudohermaphroditismSex DeterminationNine Chromatin-negative PatientsSomatic Chromosome NumberSex DifferencesPublic HealthInfertilityAndrologyCell DivisionChromosomal RearrangementSex ChromosomesSex DifferenceChromatinDevelopmental BiologyChromosome BiologyBonemarrow CultureMedicine
Nine chromatin-negative patients with varying degrees of ambiguity of sex differentiation were found to have a somatic chromosome number of 46 and an XY sex chromatin constitution in cells from bonemarrow culture. The findings are discussed in relation to Jost's theory of sex differentiation.