Prognosis Value of Residual Disease Monitoring by Polymerase Chain Reaction in Patients With CBFβ/MYH11-Positive Acute Myeloblastic Leukemia

Abstract

To the Editor: Pericentric inversion of chromosome 16, translocation (16; 16), and del(16q), resulting in a chimeric fusion of the CBFβ and MYH11 genes, are typically seen in the M4Eo French-American-British (FAB) subset of acute myelogenous leukemias (AML). Karyotypic detection of these