The role of vitamin D, estrogen, calcium sensing receptor genotypes and serum calcium in the pathogenesis of prostate cancer. - Concepedia

Concepedia

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The role of vitamin D, estrogen, calcium sensing receptor genotypes and serum calcium in the pathogenesis of prostate cancer.

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2011

Year

Attila Szendrői, Gábor Speer, Ádám G. Tabák, János P. Kósa, Péter Nyírády, Attila Majoros, Imre Romics, Péter L. Lakatos

Abstract

ER-α XbaI and VDR BsmI genetic polymorphisms had a significant association with the risk of prostate cancer. Both VDR BsmI genotypes and serum calcium levels were independently related to the risk of prostate cancer, suggesting an influence of VDR on the development of this malignancy.