Concepedia

Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages

Francesca De Falco, Carmen Di Giovanni, Carmen Cerchia, Daniela De Stefano, Antonella Capuozzo, Carlo Irace, Teresa Iuvone, Rita Santamaria, Rosa Carnuccio, Antonio Lavecchia

Biochemical Pharmacology · 2016 · 42 citations · 32 references

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32

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

Q.W. Xie, Yumiko Kashiwabara, Carl Nathan · Journal of Biological Chemistry · 1994 · 2.2K citations · Full text

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The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

Ebrahim Zandi, David M. Rothwarf, Mireille Delhase et al. · Cell · 1997 · 1.8K citations · Full text

, , +9

Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

Uwe Senftleben, Yixue Cao, Gutian Xiao et al. · Science · 2001 · 1.4K citations

, , +12

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

Shoji Yamaoka, Gilles Courtois, Christine Bessia et al. · Cell · 1998 · 1.1K citations · Full text

, , +14

Site-Specific Phosphorylation of IκBα by a Novel Ubiquitination-Dependent Protein Kinase Activity

Zhijian J. Chen, Lana Parent, Tom Maniatis · Cell · 1996 · 959 citations · Full text

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