Concepedia

Nucleus-selective Chemical Proteomics Using Hoechst-tagged Reactive Molecules

Yuki Yasueda, Tomonori Tamura, Itaru Hamachi

Chemistry Letters · 2015 · 22 citations · 7 references

DOI

Concepts

Abstract

Characterization of a nuclear proteome is a prerequisite for understanding a variety of cellular functions at the molecular level. Here, we report a novel proteomic method based on nucleus-selectiv...

References

7

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Anna E Speers, Benjamin F. Cravatt · Chemistry & Biology · 2004 · 762 citations · Full text

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SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy

Gražvydas Lukinavičius, Claudia Blaukopf, Elias Pershagen et al. · Nature Communications · 2015 · 312 citations · Full text

Disparate proteome reactivity profiles of carbon electrophiles

Eranthie Weerapana, Gabriel M. Simon, Benjamin F. Cravatt · Nature Chemical Biology · 2008 · 243 citations · Full text

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Hoechst tagging: a modular strategy to design synthetic fluorescent probes for live-cell nucleus imaging

Akinobu Nakamura, Kazumasa Takigawa, Yasutaka Kurishita et al. · Chemical Communications · 2014 · 98 citations

Selective Covalent Labeling of Tag-Fused GPCR Proteins on Live Cell Surface with a Synthetic Probe for Their Functional Analysis

Hiroshi Nonaka, Sho-hei Fujishima, Shohei Uchinomiya et al. · Journal of the American Chemical Society · 2010 · 98 citations

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