Nano hydroxyapatite particles promote osteogenesis in a three-dimensional bio-printing construct consisting of alginate/gelatin/hASCs

Abstract

To design a hydrogel material containing nano hydroxyapatite particles for three-dimensional (3D) bio-printing and to explore whether nano hydroxyapatite particles can promote osteogenic differentiation of 3D bio-printing construct consisting of hASCs <italic>in vivo</italic> and <italic>in vitro</italic>.