The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development

James P. Allinson, Rebecca Hardy, Gavin C. Donaldson, Seif O. Shaheen, Diana Kuh, Jadwiga A. Wedzicha

American Journal of Respiratory and Critical Care Medicine · 2015 · 189 citations · 41 references

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Abstract

CMH among middle-aged smokers represents an early developmental phase of chronic obstructive pulmonary disease. Smoking-related CMH usually resolves following smoking cessation but the longer its duration the greater the FEV1 lost, suggesting the course of CMH across adult life may reflect the underlying course of airway disease activity.

References

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