Journal of Bone and Joint Surgery - British Volume · 2005 · 64 citations · 25 references
Tissue EngineeringSynthetic Bone SubstituteEngineeringTricalcium PhosphateBone RemodelingBone RepairBioceramicSurgeryJoint ReplacementBiomedical EngineeringHydroxyapatite Bone-graft ExtenderMorsellised AllograftsRevision SurgeryMedicineVascularized Bone GraftOsteoporosisOrthopaedic Surgery
Impacted morsellised allografts have been used successfully to address the problem of poor bone stock in revision surgery. However, there are concerns about the transmission of pathogens, the high cost and the shortage of supply of donor bone. Bone-graft extenders, such as tricalcium phosphate (TCP) and hydroxyapatite (HA), have been developed to minimise the use of donor bone. In a human cadaver model we have evaluated the surgical and mechanical feasibility of a TCP/HA bone-graft extender during impaction grafting revision surgery. A TCP/HA allograft mix increased the risk of producing a fissure in the femur during the impaction procedure, but provided a higher initial mechanical stability when compared with bone graft alone. The implications of the use of this type of graft extender in impaction grafting revision surgery are discussed.
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THE SWEDISH TOTAL HIP REPLACEMENT REGISTER
Henrik Malchau, Peter Herberts, Thomas Eisler et al. · Journal of Bone and Joint Surgery · 2002 · 807 citations
Orthopaedic applications of hydroxyapatite
H. Oonishi · Biomaterials · 1991 · 282 citations
Tissue Engineering, Orthopaedic Biomaterials, Synthetic Bone Substitute +6