Synthesis of novel N-9 substituted 6-(4-(4-propoxyphenyl)piperazin-1-yl)-9H-purine derivatives as inducers of apoptosis in MCF-7 breast cancer cells

Abstract

A series of N-9 substituted 6-(4-(4-propoxyphenyl)piperazin-1-yl)-9<italic>H</italic>-purine derivatives (<bold>PP05–PP21</bold>) were prepared and evaluated for their anticancer activity against a panel of human cancer cell lines.