The Structure and Development of Osteogenetic Repair Tissue According to Ilizarov Technique in Man: Characterization of Extracellular Matrix

Abstract

Distraction osteogenesis by the method of Ilizarov has permitted the study of bone formation. This is an analysis of 64 human biopsies in patients who were undergoing tibial lengthening by the method of Ilizarov. After analysis by conventional and polarized light microscopy, four stages of bone formation were identified. Bone formation is of the direct type with no cartilaginous phase.