Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system

Abstract

Research Article| June 01 1972 Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system K Brocklehurst; K Brocklehurst 1Department of Biochemistry and Chemistry, St. Bartholomew's Hospital Medical College, University of London, Charterhouse Square, London EC1M 6BQ, U.K. Search for other works by this author on: This Site PubMed Google Scholar G Little G Little 1Department of Biochemistry and Chemistry, St. Bartholomew's Hospital Medical College, University of London, Charterhouse Square, London EC1M 6BQ, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1972) 128 (2): 471–474. https://doi.org/10.1042/bj1280471 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation K Brocklehurst, G Little; Reactivities of the various protonic states in the reactions of papain and of L-cysteine with 2,2′- and with 4,4′- dipyridyl disulphide: evidence for nucleophilic reactivity in the un-ionized thiol group of the cysteine-25 residue of papain occasioned by its interaction with the histidine-159-asparagine-175 hydrogen-bonded system. Biochem J 1 June 1972; 128 (2): 471–474. doi: https://doi.org/10.1042/bj1280471 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1972 London: The Biochemical Society1972 Article PDF first page preview Close Modal You do not currently have access to this content.