A one-pot process for the microwave-assisted synthesis of 7-substituted pyrazolo[1,5-a]pyrimidine

Abstract

An efficient synthesis of 7-substituted pyrazolo[1,5-<italic>a</italic>]pyrimidines using a one-pot, two-step process <italic>via</italic> Pd-catalyzed direct CH-arylation followed by a saponification–decarboxylation reaction is reported.