American Journal of Tropical Medicine and Hygiene · 1989 · 131 citations · 0 references
Veterinary MedicineImmunologyInfectious DiseasesDiagnostic MicrobiologyDiagnostic ParasitologyMedical MicrobiologyAntigen Detection AssaysHelminth DiagnosticsHelminth InfectionsHelminth PathogenesisMolecular Diagnosis Of ParasitesParasitic Disease DiagnosisAssayHelminth ImmunodiagnosisHydatid Disease DetectionHydatid Disease PathologyMolecular Diagnosis Of Parasitic InfectionsPathogenesis Of Hydatidosis
An echinococcus antigen with an apparent molecular weight of 8 kDa was identified as diagnostically important. An immunoblot assay using this antigen was 91% sensitive for surgically confirmed Echinococcus granulosus hydatid disease of the liver. Specificity was 100% for echinococcosis. Marked cross-reactivity was observed with serum specimens from patients with E. multilocularis and E. vogeli infections. The 8 kDa component was not related to the widely recognized echinococcus antigen 5.