Reduction of a subpopulation of T lymphocytes in lepromatous leprosy

Abstract

A reduction in number of a subpopulation of T lymphocytes was noted in lepromatous leprosy cases with high bacillary load. Tuberculoid and treated lepromatous patients, who were bacillary negative had normal levels of these cells. B-cell numbers were high in lepromatous patients irrespective of treatment and bacillary load.