Publication | Closed Access
SUSPENSIONS OF RADIOALBUMIN AGGREGATES FOR PHOTOSCANNING THE LIVER, SPLEEN, LUNG AND OTHER ORGANS.
152
Citations
0
References
1964
Year
Oncologic ImagingPathologyBiomedical EngineeringTreatment VerificationDiagnostic ImagingRadiation MedicinePhototoxicityCt ScanRadiopharmaceutical TherapyRadiation ImagingRadiation OncologyMolecular ImagingRadiation Medicine ImagingRadiologyHealth SciencesMedical ImagingRadiological SciencesLiver PhysiologyRadiologic ImagingRadiographic ImagingLung CancerLarge Size SuspensionsAlbumin SuspensionsRadiomicsHepatologyRadioalbumin AggregatesRadiopharmaceuticalsMedicine
Summary Current methods of preparing small and large size suspensions of radioalbumin aggregates by heat treatment and pH adjustment are presented. The small size colloidal suspensions (10–20 mµ) are shown to be superior to other agents for liver-spleen scanning. Radiation exposure to these organs is minimized and the albumin suspensions can be prepared with relative ease and simplicity. Also the heart, stomach and salivary glands may be clearly visualized by photoscanning with this material. The techniques and physiological basis for performing and interpretating scans of these organs are described. Their diagnostic value is illustrated. The preparation and physiological basis for using large size suspensions of the same material for visualization of the lungs is presented along with scans typical of those produced with suspensions of each of two size ranges (2.5 and 15 µ). The smaller size is preferable because of far less probability of capillary embolization. Trials in patients with lung cancer will be initiated after additional animal studies ensure the complete safety of the test procedure.