Publication | Closed Access
Light-controlled reactive oxygen species (ROS)-producible polymeric micelles with simultaneous drug-release triggering and endo/lysosomal escape
68
Citations
26
References
2016
Year
EngineeringEndo/lysosomal EscapeTumor BiologyAnti-cancer AgentDrug Delivery SystemPolymer ChemistryCell-based Drug DeliveryMicelle-Producible Polymeric MicellesSimultaneous Drug-release TriggeringTumor TargetingPharmacologyCell BiologyTumor TreatmentTumor MicroenvironmentBiomolecular EngineeringPolymer-drug ConjugateTherapeutic EfficacyNano-drug DeliveryAmphiphilic SystemMedicine
A doxorubicin (DOX)-loaded and light-induced ROS-producing polymeric micelle (D-LRPM), in which light triggers simultaneous DOX-release and endo/lysosomal escape, produces a powerful, spatiotemporally controllable, therapeutic efficacy for tumor treatment.
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