Concepedia

Suppression of TGF<sub>β</sub>and Angiogenesis by Type VII Collagen in Cutaneous SCC

Vera Martins, Matthew Caley, Kate M. Moore, Zsófia Szentpétery, S. Marsh, Dédée F. Murrell, M H Kim, M Avari, John A. McGrath, R. Cerio,

JNCI Journal of the National Cancer Institute · 2015 · 82 citations · 45 references

DOIFull text

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Abstract

Type VII collagen suppresses TGFβ signaling and angiogenesis in cutaneous SCC. Patients with RDEB SCC may benefit from anti-angiogenic therapy.

References

45

The Genomic Landscapes of Human Breast and Colorectal Cancers

Laura D. Wood, D. Williams Parsons, Siân Jones et al. · Science · 2007 · 2.8K citations

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A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1

John S. Munger, Xiaozhu Huang, Hisaaki Kawakatsu et al. · Cell · 1999 · 2K citations

, , +9

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

Guilian Niu, Kenneth L. Wright, Mei Huang et al. · Oncogene · 2002 · 1.2K citations

, , +5

Epidermolysis bullosa and the risk of life-threatening cancers: The National EB Registry experience, 1986-2006

Jo‐David Fine, Lorraine Johnson, Madeline Weiner et al. · Journal of the American Academy of Dermatology · 2008 · 448 citations

, , +12

Transcriptional activation of integrin β6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma

Richard C. Bates, David I. Bellovin, Courtney Brown et al. · Journal of Clinical Investigation · 2005 · 327 citations · Full text