The Drosophila hairy protein acts in both segmentation and bristle patterning and shows homology to N‐myc.

Improved tools for biological sequence comparison.

William R. Pearson, David J. Lipman · Proceedings of the National Academy of Sciences · 1988 · 11.3K citations · Full text

Life Sciences, Bioinformatics, Biology +15

Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold.

John E. Walker, M Saraste, M J Runswick et al. · The EMBO Journal · 1982 · 5.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.9K citations

Life Sciences, Genetics, Molecular Biology +14

Mutations affecting segment number and polarity in Drosophila

Christiane Nüsslein‐Volhard, Eric Wieschaus · Nature · 1980 · 4.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

Steven Henikoff · Gene · 1984 · 4.2K citations

Life Sciences, Genetics, Molecular Biology +5