Evaluation of Proteinase-Activated Receptor-1 (PAR1) Agonists and Antagonists Using a Cultured Cell Receptor Desensitization Assay: Activation of PAR2 by PAR1-Targeted Ligands

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

Thienkhai Vu, David T. Hung, V I Wheaton et al. · Cell · 1991 · 3K citations

Thrombopoiesis, Thrombosis, Signal Transduction +15

Molecular cloning of a potential proteinase activated receptor.

Sverker Nystedt, Kjell Emilsson, Claes Wahlestedt et al. · Proceedings of the National Academy of Sciences · 1994 · 884 citations · Full text

Receptor 2, Xenopus Laevis Oocytes, Immunology +17

Protease-activated receptor 3 is a second thrombin receptor in humans

Hiroaki Ishihara, Andrew J. Connolly, Dewan Zeng et al. · Nature · 1997 · 873 citations

Thrombopoiesis, Thrombosis, Signal Transduction +14

Preparation of Suspensions of Washed Platelets from Humans

J. F. Mustard, Dennis Perry, N.G. Ardlie et al. · British Journal of Haematology · 1972 · 839 citations

Thrombopoiesis, Thrombosis, Engineering +15