Concepedia

Copper-catalyzed cycloaddition between hydrogen phosphonates and activated alkenes: synthesis of phosphonoisoquinolinediones

Ju Wu, Yuzhen Gao, Xin Zhao, Liangliang Zhang, Weizhu Chen, Guo Tang, Yufen Zhao

RSC Advances · 2015 · 43 citations · 39 references

DOI

Concepts

Abstract

A new and general method for the synthesis of phosphonoisoquinolinediones has been achieved through copper-catalyzed phosphonation–cyclization of various methacryloylbenzamides with P(O)H compounds.

References

39

Direct Annulations toward Phosphorylated Oxindoles: Silver‐Catalyzed Carbon‐Phosphorus Functionalization of Alkenes

Ya‐Min Li, Meng Sun, Hongli Wang et al. · Angewandte Chemie International Edition · 2013 · 427 citations · Full text

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Arylphosphonylation and Arylazidation of Activated Alkenes

Wangqing Kong, Estı́baliz Merino, Cristina Nevado · Angewandte Chemie International Edition · 2014 · 303 citations

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6-Phosphorylated Phenanthridines from 2-Isocyanobiphenyls via Radical C–P and C–C Bond Formation

Bo Zhang, Constantin G. Daniliuc, Armido Studer · Organic Letters · 2013 · 260 citations

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Difunctionalization of Alkenes via the Visible-Light-Induced Trifluoromethylarylation/1,4-Aryl Shift/Desulfonylation Cascade Reactions

Lewei Zheng, Chao Yang, Zhaozhong Xu et al. · The Journal of Organic Chemistry · 2015 · 143 citations

, , +11

Magnesium Chelating 2-Hydroxyisoquinoline-1,3(2<i>H</i>,4<i>H</i>)-diones, as Inhibitors of HIV-1 Integrase and/or the HIV-1 Reverse Transcriptase Ribonuclease H Domain: Discovery of a Novel Selective Inhibitor of the Ribonuclease H Function

Muriel Billamboz, Fabrice Bailly, Cédric Lion et al. · Journal of Medicinal Chemistry · 2011 · 135 citations · Full text

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