Increased expression of H19/miR‐675 is associated with a low fat‐free mass index in patients with COPD

Abstract

The data suggest that increased expression of miR-675/H19 and altered methylation of the H19 imprinting control region are associated with a low FFMI in patients with COPD but not in healthy community dwelling older men suggesting that epigenetic control of this loci may contribute to a susceptibility to a low FFMI.