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IgA Nephropathy: Clinicopathology and Immunopathology
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2015
Year
Glomerular DiseaseVasculitisRenal PathologyImmunologyPathologyPrimary GlomerulonephropathiesGlomerulonephritisRenal FunctionIga GlomerulonephritisIga NephropathyImmunofluorescent FindingsChronic Kidney DiseaseAutoimmune DiseaseLupus NephritisAutoimmunityImmunologic DiseaseImmune Complex PathogenesisSclerodermaRenal DiseaseNephritic SyndromeGlomerulopathyMedicineNephrologyKidney Research
In a total of 283 biopsies, 100 (35%) were found to be IgA nephropathy. The incidence reached 40% among primary glomerulonephropathies. On the basis of histopathologic changes in glomeruli, these biopsies were classified into 3 groups. The criteria employed correlated well with clinical, laboratory and immunofluorescent findings. Immune complex pathogenesis was discussed in relation to our findings.