Lupus anticoagulants in children.

Abstract

Although a great deal of information is available in the literature on the frequency, clinical/laboratory findings and significance of lupus anticoagulants in adults, little is known about such acquired inhibitors in children. Clinical and laboratory findings are presented on seven non-hemophiliac children, four females and three males, ranging in ages from three to 14 years, who developed such inhibitors. In most, the inhibitor is a transient phenomena and is not associated with a bleeding or thrombotic diathesis.