Concepedia

Evidence for an arene-3,4-oxide as a metabolic intermediate in the meta- and para-hydroxylation of phenytoin in the dog.

M A Moustafa, Marc Claesen, Jacques Adline, Daniel Vandervorst, Jacques H. Poupaert

Drug Metabolism and Disposition · 1983 · 13 citations · 18 references

DOI

Concepts

References

18

Arene oxides and the NIH shift: The metabolism, toxicity and carcinogenicity of aromatic compounds

John W. Daly, D. M. JERINA, Bernhard Witkop · Cellular and Molecular Life Sciences · 1972 · 599 citations

, , +10

Deuterium isotope effects during formation of phenols by hepatic monoxygenases. Evidence for an alternative to the arene oxide pathway

Joseph E. Tomaszewski, D. M. JERINA, John W. Daly · Biochemistry · 1975 · 147 citations

, , +14

The Replacement of Phenolic Hydroxyl Groups by Hydrogen

Walter J. Musliner, J. W. Gates · Journal of the American Chemical Society · 1966 · 102 citations

, , +9

Migration of deuterium during hydroxylation of aromatic substrates by liver microsomes: I. Influence of ring substituents

John W. Daly, Donald M. Jerina, Bernhard Witkop · Archives of Biochemistry and Biophysics · 1968 · 92 citations

, , +13

A new metabolite of 5,5-diphenylhydantoin (Dilantin++Dilantin is the Parke-Davis trade name for 5,5-diphenylhydatoin (phenytoin).)

Tsun Chang, Ardis Savory, Anthony J. Glazko · Biochemical and Biophysical Research Communications · 1970 · 91 citations

, , +3