Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients - Concepedia

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Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients

DOI Full Paper Access

49

Citations

42

References

2015

Year

Scott Maynard, Anne‐Mette Hejl, Thuan-Son T. Dinh, Guido Keijzers, Åse Marie Hansen, Claus Desler, María Moreno‐Villanueva, Alexander Bürkle, Lene Juel Rasmussen, Gunhild Waldemar,

Abstract

This study reveals impaired mitochondrial respiration, altered dNTP pools and reduced DNA repair activity in PBMCs of AD patients, thus suggesting that these biochemical activities may be useful as biomarkers for AD.

References

	Year	Citations

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