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Simultaneous determination of ledipasvir, sofosbuvir and its metabolite in rat plasma by UPLC–MS/MS and its application to a pharmacokinetic study

Pharmaceutical SciencePharmacologyPharmacokinetic StudyAntiviral Drug DevelopmentAntiviral TherapyAnalytical ChemistrySimultaneous DeterminationAntiviral DrugMetabolomicsMedicineRat PlasmaPharmacokineticsChromatographyDrug Analysis