Hydrophobic interactions between the S5 segment and the pore helix stabilizes the closed state of Slo2.1 potassium channels

Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution

Yufeng Zhou, João H. Morais‐Cabral, Amelia Kaufman et al. · Nature · 2001 · 2.1K citations

Ion Coordination, Inorganic Chemistry, Engineering +9

Increasing the precision of comparative models with YASARA NOVA—a self‐parameterizing force field

Elmar Krieger, Günther Koraimann, Gert Vriend · Proteins Structure Function and Bioinformatics · 2002 · 1.5K citations · Full text

Energetic optimization of ion conduction rate by the K+ selectivity filter

João H. Morais‐Cabral, Yufeng Zhou, Roderick MacKinnon · Nature · 2001 · 847 citations

Ion Conduction Rate, Chemical Engineering, Electrical Engineering +12

Mutations in the K+ channel signature sequence

Lise Heginbotham, Zheming Lu, Tatiana Abramson et al. · Biophysical Journal · 1994 · 832 citations · Full text

Channelopathies, Genetics, Signal Recognition +5

The Cavity and Pore Helices in the KcsA K ⁺ Channel: Electrostatic Stabilization of Monovalent Cations

Benoı̂t Roux, Roderick MacKinnon · Science · 1999 · 434 citations