Concepedia

Improved therapeutic activity of HER2 Affibody-targeted cisplatin liposomes in HER2-expressing breast tumor models

Seyedeh Hoda Alavizadeh, Javad Akhtari, Ali Badiee, Shiva Golmohammadzadeh, Mahmoud Reza Jaafari

Expert Opinion on Drug Delivery · 2015 · 49 citations · 41 references

DOI

Abstract

Affibody-targeting endowed cisplatin liposomes with significantly enhanced, albeit modest, therapeutic activity in HER2-overexpressing tumor model; however, further values are yet to be determined to advance clinical translation of these targeted nanoparticulates.

References

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Phosphorus Assay in Column Chromatography

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Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2

Dennis J. Slamon, Brian Leyland‐Jones, Steven Shak et al. · New England Journal of Medicine · 2001 · 11.4K citations · Full text

Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease

Melody Cobleigh, Charles L. Vogel, Debu Tripathy et al. · Journal of Clinical Oncology · 1999 · 2.8K citations

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Theresa M. Allen, Cecilie Cetti Hansen · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 570 citations

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Tumor Imaging Using a Picomolar Affinity HER2 Binding Affibody Molecule

Anna Orlova, Mikaela Magnusson, Tove Eriksson et al. · Cancer Research · 2006 · 555 citations · Full text