American Journal of Tropical Medicine and Hygiene · 1982 · 102 citations · 0 references
Veterinary MedicineBiologyInfectious DiseasesDiagnostic ParasitologyInfectious Disease PathologyParasitologyAntigen Detection AssaysMedical ParasitologyNeurological Parasitic DiseasesParasitic Disease DiagnosisParasitic ZoonosesZoonotic Parasitic DiseasesParasite Antibody DetectionParasitic Antigen DetectionParasitic DetectionParasitic DiagnosisParasitic SerologySerological Diagnosis Of Parasitic InfectionsSerology For Parasitic DiseasesTaenia Solium Detection
An enzyme-linked immunosorbent assay (ELISA) for the detection of antibody to cysticerci of Taenia solium has been developed that employs a pork muscle antigen control for the cysticercus test antigen, somewhat improving the serological distinction between infected and uninfected subjects. Serum antibody to cysticercus was detected in 79% of classical neurocysticercosis patients from Mexico, and in 61% of a group of cysticercosis patients with an unusually rapid invasion of the central nervous system in an endemic focus of disease in Irian Jaya. Antibody was absent in a group of healthy American laboratory personnel, and in residents of a non-endemic region of Papua New Guinea. Additional test on sera from patients with other parasitic diseases showed that cross-reactivity may occur in some patients with schistosomiasis, echinococcosis, and possibly angiostrongyliasis; however, these parasites are not known to cause human infection in Irian Jaya.