Peritoneal Fluid and Tracer Albumin Kinetics in the Rat. Effects of Increases in Intraperitoneal Hydrostatic Pressure

Abstract

At a nearly unchanging capillary Starling equilibrium, the losses of fluid and of RISA from the PC were markedly elevated at increased IPPs. However, the RISA clearance to the plasma appeared to be only moderately altered at elevated IPP and represented only a minor fraction of the RISA clearance out of the PC. Tissues lining the PC apparently act as a variable 'sink' for intraperitoneal proteins and fluid during peritoneal dialysis (PD).