Structure–activity relationship studies of c-di-AMP synthase inhibitor, bromophenol-thiohydantoin

c-di-AMP Secreted by Intracellular <i>Listeria monocytogenes</i> Activates a Host Type I Interferon Response

Joshua J. Woodward, Anthony T. Iavarone, Daniel A. Portnoy · Science · 2010 · 802 citations · Full text

Microbial Pathogens, Innate Immune System, Immunology +23

c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress

Rebecca M. Corrigan, James Abbott, Heike Burhenne et al. · PLoS Pathogens · 2011 · 467 citations · Full text

Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates

Gregor Witte, Sophia Hartung, Katharina Büttner et al. · Molecular Cell · 2008 · 427 citations · Full text

Natural Sciences, Molecular Biology, Dna Replication +7

Riboswitches in eubacteria sense the second messenger c-di-AMP

James W. Nelson, Narasimhan Sudarsan, Kazuhiro Furukawa et al. · Nature Chemical Biology · 2013 · 284 citations · Full text

Bacteriology, Bacteriophage, Molecular Biology +3

Privileged Scaffolds or Promiscuous Binders: A Comparative Study on Rhodanines and Related Heterocycles in Medicinal Chemistry

Thomas Mendgen, Christian Steuer, Christian D. Klein · Journal of Medicinal Chemistry · 2011 · 282 citations

High Density, Combinatorial Chemistry, Medicinal Chemistry +15