Kidney ischaemia reperfusion injury in the rat: the EGTI scoring system as a valid and reliable tool for histological assessment

Abstract

Introduction Ischaemia reperfusion injury (IRI) is a complex pathological process characterized by initial restriction of blood supply to the organ followed by subsequent restoration of blood flow and oxygenation, and is an inevitable consequence of organ transplantation, causing significant morbidity and mortality. In kidney transplantation, IRI manifests as primary non-function and