Systemic sarcoidosis associated with interferon-alpha treatment for chronic myelogenous leukemia.

Abstract

We describe a patient with chronic myeloid myeloid leukemia (CML) on tow-dose treatment with interferon (IFN) who developed systemic sarcoidosis, a rare IFN-related side effect, while in complete cytogenetic remission. We chose to continue IFN and to treat the sarcoidosis with prednisone. After eight months, the CML is still in complete cytogenetic remission and the sarcoidosis is almost completely resolved.