Publication | Open Access
PD-L1 biology in response to chemotherapy in vitro and in vivo in ovarian cancer
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2015
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ImmunologyImmune Cell TherapyImmune SystemCancer BiologyImmunotherapyTumor BiologyOvarian CancerTumor ImmunologyOncologyTumor ImmunityRadiation OncologyAbstracts Pd-l1Cancer TreatmentImmune Checkpoint MoleculeCell BiologyPd-l1 BiologyCancer ImmunosurveillanceImmune Checkpoint InhibitorMedicine
Meeting abstracts PD-L1 is an immune checkpoint molecule expressed by a variety of tumors, including ovarian, which binds to circulating PD-1 expressing effector T cells allowing for tumor escape from the immune system. PD-L1 blockade prevents PD-L1/PD-1 interaction and is currently explored as