Antitubercular Lanostane Triterpenes from Cultures of the Basidiomycete <i>Ganoderma</i> sp. BCC 16642

Masahiko Isaka, Panida Chinthanom, Malipan Sappan, Kannawat Danwisetkanjana, Thitiya Boonpratuang, Rattaket Choeyklin

Journal of Natural Products · 2015 · 40 citations · 16 references

Concepts

Abstract

Sixteen new lanostane triterpenoids (1-16), together with 26 known compounds (17-42), were isolated from cultures of the basidiomycete Ganoderma sp. BCC 16642. Antitubercular activities of these Ganoderma lanostanoids against Mycobacterium tuberculosis H37Ra were evaluated, and structure-activity relationships are proposed.

References

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