Nationwide Study of Humidifier Disinfectant Lung Injury in South Korea, 1994–2011. Incidence and Dose–Response Relationships

Abstract

Dose-response analysis indicated that development of humidifier disinfectant lung injury and death were associated strongly with recurrent, intense, acute exposure without sufficient recovery time between exposures, more so than long-term cumulative exposure. These findings may explain some reversible or clinically unapparent cases among coexposed family members.