Enhancement of oxaliplatin sensitivity in human colorectal cancer by hypericin mediated photodynamic therapy via ROS-related mechanism

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

David Ron, Joel F. Habener · Genes & Development · 1992 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.

Toshihisa Ishikawa, Francis Ali‐Osman · Journal of Biological Chemistry · 1993 · 538 citations · Full text

Medicine, Biochemistry, Pharmacology +16

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

Guido J.R. Zaman, J. Lankelma, Olaf van Tellingen et al. · Proceedings of the National Academy of Sciences · 1995 · 502 citations · Full text

Medicine, Oncology, Pharmacology +16

Oxaliplatin-Induced Damage of Cellular DNA

Jan M. Woynarowski, Sandrine Faivre, Maryanne C. Herzig et al. · Molecular Pharmacology · 2000 · 300 citations

Pharmacy, Molecular Biology, Oncology +17

Efficient nucleotide excision repair of cisplatin, oxaliplatin, and Bis-aceto-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) platinum intrastrand DNA diadducts.

Joyce T. Reardon, Alexandra Vaisman, Stephen G. Chaney et al. · PubMed · 1999 · 288 citations

Medicine, Molecular Biology, Oncology +13