Concepedia

Implications for blood-brain-barrier permeability, in vitro oxidative stress and neurotoxicity potential induced by mesoporous silica nanoparticles: effects of surface modification

Ming Zhou, Linlin Xie, Chen‐Jie Fang, Hua Yang, Yanjie Wang, Xiaoyu Zhen, Chun‐Hua Yan, Yuji Wang, Ming Zhao, Shiqi Peng

RSC Advances · 2015 · 42 citations · 43 references

DOI

Concepts

Abstract

MSNs are shown to have the potential to overcome the BBB and cause neuronal damage. However, the neurotoxicity potential could be mediated with surface modification.

References

43

A new family of mesoporous molecular sieves prepared with liquid crystal templates

Jeffrey S. Beck, J.C. Vartuli, Wiesław J. Roth et al. · Journal of the American Chemical Society · 1992 · 10.9K citations

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Mitochondrial formation of reactive oxygen species

Julio F. Turrens · The Journal of Physiology · 2003 · 3.9K citations

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Translocation of Inhaled Ultrafine Particles to the Brain

Günter Oberdörster, Z. D. Sharp, Viorel Atudorei et al. · Inhalation Toxicology · 2004 · 2.6K citations

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Comparison of the Abilities of Ambient and Manufactured Nanoparticles To Induce Cellular Toxicity According to an Oxidative Stress Paradigm

Tian Xia, Michael Kovochich, Jonathan A. Brant et al. · Nano Letters · 2006 · 1.9K citations

, , +16

Identification of ROS Using Oxidized DCFDA and Flow-Cytometry

Evgeniy Eruslanov, Sergei Kusmartsev · Methods in molecular biology · 2009 · 1.3K citations

, , +11