Perinatal Phosphatidylcholine Supplementation and Early Childhood Behavior Problems: Evidence for <i>CHRNA7</i> Moderation

Abstract

CHRNA7, the α7-nicotinic acetylcholine receptor gene, has been associated with schizophrenia, autism, and attention deficit hyperactivity disorder. Maternal phosphatidylcholine treatment may, by increasing activation of the α7-nicotinic acetylcholine receptor, alter the development of behavior problems in early childhood that can presage later mental illness.