International Journal of Otolaryngology · 2015 · 24 citations · 15 references
Life SciencesImmunologyPathologyClinical ImmunologyImmunopathologyNeuroimmunologyFacial Nerve DisordersNeutrophil BiologyControl Group DesignHouse-brackmann GradingLymphocyte SubtypesMatched Control GroupNeutrophil InvolvementNeutrophil-to-lymphocyte RatioPrognostic BiomarkersRetrospective Case Study
Objective. The purpose of this study was to investigate whether or not there was a correlation between the neutrophil-to-lymphocyte ratio (NLR) value and the severity of idiopathic peripheral facial palsy (IPFP) and to determine whether or not NLR could be used as an early predictive parameter in the prognosis of IPFP patients. Material and Method. This retrospective study was conducted on 146 patients who were diagnosed with IPFP. The control group comprised 140 patients. Patients with IPFP were categorized according to the House-Brackmann grading system (HBS). The NLR value was obtained by dividing the neutrophil value by the lymphocyte value. Results. In the IPFP group, the mean NLR value was 3.63 ± 2.74 and, in the control group, 1.84 ± 0.78. The mean NLR value was significantly higher in IPFP patients than in the control subjects (p < 0.0001). The mean NLR value in group A (Grades I-II ) was 2.61 ± 2.28, in group B (Grades III-IV) 3.22 ± 2.65, and in group C (Grades V-VI) 10.69 ± 6.30. Conclusion. We determined that as the severity of IPFP increased, the NLR value increased. The NLR value can be used as a prognostic factor in the early prediction of IPFP prognosis.
15
Early Treatment with Prednisolone or Acyclovir in Bell's Palsy
Frank Sullivan, Iain Swan, Peter T. Donnan et al. · New England Journal of Medicine · 2007 · 755 citations · Full text
Valacyclovir and Prednisolone Treatment for Bell's Palsy
Naohito Hato, Hiroyuki Yamada, Hisashi Kohno et al. · Otology & Neurotology · 2007 · 248 citations
Early Treatment with Prednisolone or Acyclovir in Bell’s Palsy
Frank Sullivan, Iain Swan, Peter T. Donnan et al. · Clinical Otolaryngology · 2007 · 102 citations