Small · 2015 · 87 citations · 44 references
PharmacyNeuroscienceRadiologyBiomedical ImagingDrug DeliveryNanoparticle Drug DeliveryContrast AgentsContrast MediaMagnetic Resonance ImagingMedical ImagingMultimodal ImagingNanomedicineContrastMagnetic ResonanceMagnetic Resonance Imaging Contrast AgentsMagnetic Resonance PhysicsManganese Oxide NanomaterialsManganese-based Contrast AgentsNanoparticle Contrast AgentsNanoparticle-based Contrast Agents
Manganese oxide nanoparticles (MONPs) are capable of time-dependent magnetic resonance imaging contrast switching as well as releasing a surface-bound drug. MONPs give T2/T2* contrast, but dissolve and release T1-active Mn2+ and L-3,4-dihydroxyphenylalanine. Complementary images are acquired with a single contrast agent, and applications toward Parkinson's disease are suggested. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Byung Hyo Kim, Nohyun Lee, Hyoungsu Kim et al. · Journal of the American Chemical Society · 2011 · 942 citations
Natural Sciences, Materials Engineering, Materials Science +17